
Erythritol May Weaken Brain’s Shield, Linked to Stroke Risk in Lab Study
A laboratory study found that erythritol can damage brain endothelial cells by lowering nitric oxide, raising endothelin-1 and reactive oxygen species, and reducing tissue plasminogen activator, which together may weaken the blood-brain barrier and help explain links between higher erythritol levels and stroke risk. The work was done in cell cultures, not humans, so results must be interpreted with caution and more clinical research is needed; researchers also urge monitoring non-nutritive sweetener consumption.













