All articles tagged with #anti ageing
A growing wave of anti-ageing therapies—metformin, senolytics, rapamycin and others—may slow aging and extend healthy years, with big trials like TAME aiming to treat ageing as a condition; while animal studies look promising, human trials are long, costly, and hampered by regulatory and funding hurdles.
A clinical trial has found that the diabetes drug henagliflozin not only lowers blood sugar but also has anti-ageing effects by increasing telomere length, which are protective chromosomal caps that shorten with age.
The article discusses eight common beauty mistakes that can accelerate ageing and offers tips on how to avoid them to maintain a youthful appearance.
A simple exercise like squats, especially chair squats, can effectively maintain strength, flexibility, and independence in older adults without the need for a gym, supporting healthy ageing and functional mobility.
A new study shows that rapamycin extends lifespan almost as effectively as calorie restriction in animals, unlike metformin, which shows no clear benefit. While promising, more research is needed to confirm safety and efficacy in humans, and current evidence is primarily from animal studies.
Peptides are emerging as a popular, low-cost alternative to traditional anti-ageing treatments among middle-aged men, touted for their ability to boost recovery, build muscle, and improve vitality. While some peptides have established medical uses, others are used off-label with potential risks, and experts advise consulting a doctor before use. The trend is partly driven by social media influence and a desire to maintain energy and youthfulness, with some high-profile advocates like Bryan Johnson exploring their potential.
Pilates, a century-old exercise method, is praised for its anti-ageing benefits, enhancing muscle strength, and improving posture. Suitable for all fitness levels, it focuses on spinal alignment and strengthening deep postural muscles, potentially reducing injury risk and supporting cognitive and bone health. Pilates can be practiced at home or in studios, making it accessible to everyone. However, individuals with specific health concerns should consult professionals before starting.
Scientists have discovered that a drug targeting the protein interleukin-11 can extend the lifespan of laboratory mice by up to 25%, making them healthier and less prone to cancer. The drug, which is already being tested in humans for lung fibrosis, shows promise for slowing human ageing, though its effectiveness and safety in people remain uncertain.
The resignation of Harvard scientist David Sinclair, a key figure in NAD therapy research, has cast doubts on the efficacy of anti-ageing treatments, potentially impacting China's booming NMN supplement industry. Despite Sinclair's controversial claims and financial conflicts of interest, Chinese companies like GeneHarbor have significantly reduced NMN production costs, making the supplements more accessible. However, regulatory hurdles and scientific skepticism continue to challenge the industry's growth.
Dave Pascoe, a 61-year-old anti-ageing influencer, claims to have reversed his biological clock by taking 150 supplements a day and following a holistic regime that includes avoiding toxins, an infrared sauna, and cold exposure, costing him $30,000 a year. He aims to equalize his healthspan and lifespan, and is currently ranked sixth in the world Rejuvenation Olympics. Meanwhile, Bryan Johnson, 46, is spending $2m a year on a futuristic plan involving 30 doctors to achieve his goal of becoming 18 again, including extensive medical tests, cosmetic procedures, and a focus on sleep, exercise, and healthy eating.
Scientists have discovered that biological age can differ from chronological age, and it can be influenced by lifestyle choices. Maintaining muscle, following a balanced diet, good oral hygiene, adequate sleep, and protecting eyes and skin from UV light are all factors that can help slow down the ageing process. Additionally, future super drugs targeting the hallmarks of ageing offer promise for extending healthspan.
Lifestyle habits can influence how our genes are expressed, potentially affecting longevity. Studies suggest that calorie restriction, exercise, and sleep can activate genes linked to long life, such as mTOR and FOXO3. Research also indicates that green tea, quercetin, and certain dietary habits can influence genetic expression associated with longevity. While genetic predispositions play a role, lifestyle choices can significantly impact gene expression and overall health.
Dr. Michael Greger's new book "How Not To Age" provides insights on how to slow down the ageing process through simple dietary tweaks, such as consuming hot cocoa for skin health and incorporating phytoestrogen-rich foods like flaxseeds to manage menopausal symptoms. Additionally, maintaining a healthy weight through a plant-based diet can lead to longer life, while maximizing antioxidant intake from fruits and vegetables can help combat hair greying. Forest bathing, sufficient sleep, and consuming immune-boosting foods like blueberries, broccoli, and seaweed are also recommended for overall wellness.
Scientists have discovered a breakthrough in anti-ageing research, revealing that reprogrammed T cells known as CAR T cells can slow and even reduce the effects of ageing by targeting and eliminating senescent cells responsible for age-related conditions and diseases. The treatment, dubbed the 'living drug', has shown promising results in mice, with potential long-lasting effects after a single dose. This discovery could revolutionize anti-ageing therapies and pave the way for a healthier and potentially longer life.
Chinese scientists claim to have developed a new anti-ageing therapy using hydrogen that can potentially reverse the ageing process and prevent diseases like Alzheimer's. The therapy involves delivering a high concentration of hydrogen molecules through a scaffold implant, which is 40,000 times more efficient than previous methods. The implant releases hydrogen slowly and consistently for up to nine days, showing promising results in repairing bone defects in older mice. While more research is needed, the scientists believe that continuous hydrogen supply could be a universal anti-ageing technology with various applications.