Tag

Genetic Risk

All articles tagged with #genetic risk

health10 days ago•2 min saved

Four Family Health Patterns Doctors Want You to Track

Dr. Akshay Syal, an internal medicine physician and NBC News contributor, outlines four key indicators in family medical history that may signal elevated health risks. These include diseases diagnosed at unusually young ages, multiple relatives on the same side of the family sharing a condition, specific cancer patterns, and known genetic mutations. Identifying these factors allows doctors to adjust screening schedules and prevention strategies, though they do not guarantee the development of a disease.

via TODAY.com|

#family-health #genetic-risk #health

science9 months ago•6 min saved

Rapid Mutations in Aging Sperm Surprise Scientists

New research shows that harmful genetic mutations in sperm increase with age and are actively favored during sperm production, raising genetic risks for offspring as men grow older, with some mutations linked to serious diseases and cancer, and evidence of natural selection within the testes influencing mutation rates.

via SciTechDaily|

#aging #genetic-risk #mutations

health10 months ago•8 min saved

Mother and Daughter Both Battle Breast Cancer

The article discusses the emotional and psychological toll of breast cancer diagnoses within a family, highlighting cases of multiple family members affected, the role of genetic mutations like BRCA, and the different experiences of women diagnosed at various ages, emphasizing the importance of support and awareness.

via The Guardian|

#breast-cancer #family-impact #genetic-risk

science11 months ago•3 min saved

Age-Related Increase in Genetic Mutations in Men's Sperm

A study shows that sperm from older men carry more genetic mutations, including potentially harmful ones, which increases the risk of genetic diseases in offspring. The research highlights that mutations accumulate with age and are subject to positive selection, raising concerns about reproductive planning and genetic counseling for older fathers.

via WIRED|

#genetic-mutations #genetic-risk #mutation-accumulation

science11 months ago•5 min saved

Age-Related Increase in Harmful Mutations in Men's Sperm

Research shows that as men age, harmful genetic mutations in sperm become more common due to natural selection favoring certain DNA changes, increasing the risk of passing on genetic disorders to offspring, with implications for reproductive health and genetic inheritance.

via Science Daily|

#genetic-mutations #genetic-risk #inheritance

health1 year ago•4 min saved

Revolutionizing Pregnancy with Whole-Genome Sequencing

Whole-genome sequencing is set to revolutionize pregnancy by enabling embryo screening to reduce genetic risks, potentially transforming IVF practices, but raising ethical and accessibility concerns.

via WIRED|

#embryo-screening #ethical-concerns #genetic-risk

health-and-science1 year ago•94 min saved

Genetic Insights Reveal Microglial Changes and Lipid Droplet Accumulation in Alzheimer’s Risk

The study identifies a functional Alzheimer's disease risk variant in the PICALM gene that disrupts PU.1 binding, reduces PICALM expression in microglia, leading to increased lipid droplet accumulation, lysosomal dysfunction, and impaired phagocytosis, which may contribute to disease pathology.

via Nature|

#alzheimers #genetic-risk #health-and-science

health1 year ago•4 min saved

Brain Structure Tied to Genetic Risk of Major Depression

A large-scale study found that individuals with a higher genetic risk for major depression, measured by polygenic risk scores, tend to have smaller brain volumes and surface areas in specific regions such as the hippocampus, thalamus, and orbitofrontal cortex, with potential implications for early intervention and personalized treatment.

via Medical Xpress|

#brain-structure #genetic-risk #health

health1 year ago•3 min saved

Mediterranean Diet May Reduce Genetic Risk of Dementia

A study shows that following the Mediterranean diet can significantly reduce the risk of dementia, especially in individuals with a high genetic risk for Alzheimer's disease due to the APOE4 gene, suggesting that diet can help mitigate genetic predispositions.

via SELF Magazine|

#alzheimers #dementia #genetic-risk

health1 year ago•8 min saved

Should You Discover Your Genetic Risk for Alzheimer's?

The article discusses the implications of discovering your genetic risk for Alzheimer's disease, particularly the APOE4 gene, highlighting that while genetic testing can inform about increased risk, lifestyle choices such as sleep, exercise, diet, and inflammation management play a crucial role in mitigating this risk. It emphasizes that genes are not destiny and encourages proactive health habits regardless of genetic results.

via MindBodyGreen|

#alzheimers #apoe4 #brain-health

health1 year ago•3 min saved

Increased Social Activity in Midlife May Signal Early Alzheimer’s Risk

A study suggests that in early stages, individuals with a higher genetic risk for Alzheimer's may become more socially engaged and have better family relationships, possibly as a compensatory response, challenging the idea that social isolation increases Alzheimer's risk.

via Neuroscience News|

#alzheimers #early-stages #genetic-risk

health1 year ago•4 min saved

Marathon Runner Faces Final Christmas After Ignoring Cancer Warning Signs

Lee Rawlinson, a 51-year-old marathon runner from Essex, was diagnosed with terminal pancreatic cancer despite having normal blood tests. Initially attributing his abdominal pain to stress, Rawlinson later discovered the cancer had spread to his liver, making it inoperable. With a family history of the disease, he emphasizes the importance of recognizing symptoms and genetic risks. Rawlinson is now focused on creating lasting memories with his family and raising awareness about pancreatic cancer, which remains one of the deadliest cancers with limited treatment options.

via Daily Mail|

#family #genetic-risk #health

health1 year ago•4 min saved

Simple Steps to Lower Dementia Risk

A Lancet commission report suggests that 40% of dementia cases could be delayed or prevented by addressing 14 modifiable risk factors. Dr. Jonathan Rosand and his team have developed a 'brain care score' to help individuals track and improve their brain health through lifestyle changes such as diet, exercise, and stress management. Studies show that a higher brain care score is linked to a lower risk of dementia, stroke, and depression, even for those with genetic predispositions. The score emphasizes the importance of healthy habits and managing chronic conditions.

via NPR|

#brain-health #dementia #genetic-risk

health1 year ago•2 min saved

Exercise Linked to Lower Dementia Risk, Even for Genetically Prone

A Swedish study suggests that regular exercise to improve cardiorespiratory fitness (CRF) may reduce the risk of dementia, even in individuals genetically predisposed to the condition. The research, involving over 61,200 participants from the UK Biobank, found that high CRF delayed dementia onset by 1.5 years and reduced risk by 35% in those with moderate-to-high genetic risk. While the study highlights a link rather than causation, it suggests enhancing CRF could be a preventive strategy against dementia.

via Newsmax|

#alzheimers-disease #cardiorespiratory-fitness #dementia

health1 year ago•2 min saved

Boosting Fitness Levels May Lower Dementia Risk, Studies Suggest

Research published in the British Journal of Sports Medicine indicates that higher cardiorespiratory fitness (CRF) can significantly reduce the risk of dementia, even in individuals genetically predisposed to the condition. The study, involving over 61,000 participants, found that those with the highest CRF had better cognitive function and a 35% lower risk of dementia. The findings suggest that maintaining physical fitness could delay the onset of dementia by nearly 18 months, highlighting exercise as a crucial component of a healthy lifestyle to mitigate dementia risk.

via The Guardian|

#alzheimers-disease #cognitive-function #dementia