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Electron Microscopy

All articles tagged with #electron microscopy

Bruker’s GAIA Microscope Set to Ship for Ultra-Cold Quantum Imaging
science-and-technology17 days ago

Bruker’s GAIA Microscope Set to Ship for Ultra-Cold Quantum Imaging

Bruker is set to ship its first scanning transmission electron microscope (STEM) capable of stable operation near absolute zero to three global labs by early 2027. Dubbed GAIA, the instrument uses liquid helium to cool samples to approximately 7 kelvin for over 30 hours, enabling atomic-resolution imaging of quantum materials. This breakthrough addresses decades-long challenges in cryogenic microscopy, where previous liquid helium attachments suffered from rapid evaporation and vibration-induced blurring. By integrating cooling directly into the microscope and adding aberration correction and a monochromator, GAIA allows researchers to observe material properties at ultra-low temperatures without the instability that previously limited data collection.

Second Fruit Fly Brain Connectome Complete, Paving Way for Neurobiology
science1 month ago

Second Fruit Fly Brain Connectome Complete, Paving Way for Neurobiology

Researchers completed the second complete connectome of a fruit fly brain: the male Drosophila connectome (≈150,000 neurons and >300 million synapses) was mapped over about four years using serial electron microscopy, AI-powered stitching and segmentation, and human proofreading in a Janelia–Google collaboration. It follows a female connectome finished earlier this year and should accelerate neurobiology research while enabling new insights into sex differences, including 289 male-specific neurons, 71 female-specific neurons, and 138 shared neurons wired differently.

DIY SEM-to-TEM Converter Demonstrates Budget-Friendly Upgrade
technology3 months ago

DIY SEM-to-TEM Converter Demonstrates Budget-Friendly Upgrade

A technical project shows how a scanning electron microscope can be converted into a transmission electron microscope using a custom, thinner sample plate and a reworked, space-saving sample holder to free clearance for the primary electron mirror and secondary-electron shield. By dialing in the mirror angle inside the evacuated chamber, the DIY adapter yields improved TEM imaging, with initial tests using gold nanoparticles and iterative shielding tweaks enhancing image quality—an approach that echoes other STEM-converter efforts and aims to later image biological cells while offering a cost-effective alternative to pricey commercial adapters.

Picometer-precision atom steering yields mesoscopic defect crystal in CrSBr
science4 months ago

Picometer-precision atom steering yields mesoscopic defect crystal in CrSBr

Researchers demonstrate deterministic atomic engineering inside CrSBr by steering Cr atoms with sub-20-pm accuracy to create a mesoscopic 3D defect crystal (~40,000 defects) within a 150×100×13 nm volume. The engineered lattice is stable at room temperature and opens routes for deterministic colour-centre placement, quantum simulations of many-body systems, and scalable atomic-scale manufacturing outside the microscope.

Lab Breakthrough Grows Dolomite, Solving a 200-Year Mineral Mystery
science5 months ago

Lab Breakthrough Grows Dolomite, Solving a 200-Year Mineral Mystery

Scientists finally managed to grow dolomite in the lab after 32 straight failed attempts spanning two centuries. The breakthrough came from a hybrid approach that combined computational modeling of atomic arrangements with an in-situ technique that uses a pulsed electron beam to remove defects under fluctuating supersaturation. This enabled the controlled growth of about 300 dolomite layers (roughly 100 nanometers), solving the long-standing “dolomite problem” and potentially enabling dolomite-based advances in cement, batteries, semiconductors, and solar panels.

Dolomite Mystery Cracked: Lab-Grown Crystals Form by Dissolving Defects
science5 months ago

Dolomite Mystery Cracked: Lab-Grown Crystals Form by Dissolving Defects

Researchers from the University of Michigan and Hokkaido University have solved the two-century Dolomite Problem by showing that dolomite growth is defect-limited and those defects can be dissolved away, mimicking natural weathering. Using atomic-scale simulations and pulsed electron-beam dissolution, they grew dolomite to about 100 nanometers (roughly 300 layers), a dramatic advance from previous attempts. This breakthrough not only explains dolomite abundance in ancient rocks but also offers a new approach to defect-free crystal growth for modern technologies like semiconductors, solar cells, and batteries.

Scientists Discover Coffee as a Safer Staining Agent for Electron Microscopy
science9 months ago

Scientists Discover Coffee as a Safer Staining Agent for Electron Microscopy

Researchers discovered that espresso coffee can effectively stain biological samples for electron microscopy, offering a safe, inexpensive, and non-toxic alternative to traditional heavy metal stains like uranyl acetate, with promising results in imaging zebrafish mitochondria, though further testing across different tissues is needed.

New Study Challenges Traditional Views on Neuron Structure
science1 year ago

New Study Challenges Traditional Views on Neuron Structure

A study using advanced electron microscopy reveals that axons, previously thought to be tube-like, have a "pearl-on-a-string" structure, termed "non-synaptic varicosities." This discovery, which may impact brain signaling and neurodegenerative disease research, shows that axon morphology is influenced by membrane mechanics, such as cholesterol levels. The findings challenge long-held beliefs about neuron structure and suggest potential revisions in biology textbooks.

"Chiral Electron Paths: A Twist in Physics Revolutionizing Technology"
physics2 years ago

"Chiral Electron Paths: A Twist in Physics Revolutionizing Technology"

Researchers in Germany have successfully sent single electrons along structured chiral paths, achieving chirality in electron matter waves without angular momentum. This work, which parallels earlier research with photons, could have significant applications in electron microscopy and the study of magnetic materials. However, some scientists are skeptical about the claim of chirality without angular momentum and the lack of citation of previous related work.

"Revolutionary Laser Technique Could Transform Future Technology"
science-and-technology2 years ago

"Revolutionary Laser Technique Could Transform Future Technology"

Physicists at the University of Konstanz have discovered a method to imprint chirality onto electrons using laser light, creating chiral coils of mass and charge. This breakthrough has significant implications for quantum optics, particle physics, and electron microscopy, potentially leading to new scientific explorations and technological advancements.

"Revealing the Origin of Life: Insights from the Winchcombe Meteorite"
science2 years ago

"Revealing the Origin of Life: Insights from the Winchcombe Meteorite"

Researchers have discovered pristine extraterrestrial organic molecules, including amino acids and nucleobases, inside the Winchcombe meteorite, shedding light on the potential contributions to the development of life on Earth. This marks a significant advancement in understanding the solar system's formation and the role of carbonaceous meteorites in delivering organic compounds to the early Earth. The findings, published in Nature Communications, were made possible through advanced electron microscopy analysis, providing unprecedented resolution and efficiency in analyzing extraterrestrial organic matter.

"Revolutionizing Electron Microscopy: High-Resolution Imaging on a Budget"
science-and-technology2 years ago

"Revolutionizing Electron Microscopy: High-Resolution Imaging on a Budget"

Researchers at the University of Illinois Urbana-Champaign have demonstrated that record-breaking microscopic resolution can be achieved using electron ptychography on "conventional" transmission electron microscopes, breaking the trend of increasing microscope price with increasing resolution. This new technique, which uses computation to boost resolution, allows for deep sub-angstrom spatial resolution and rivals the highest ptychographic resolutions achieved with expensive aberration-corrected microscopes. The approach quadruples the resolution of conventional transmission electron microscopes and represents a significant paradigm shift in the field of electron microscopy.