
Ancient hybrid between tomato and a tuberless relative created the potato’s distinctive tuber
Genomic analysis published in Cell (2025) shows the potato lineage arose from an ancient hybrid between a tomato-lineage ancestor and an Etuberosum ancestor about 8–9 million years ago in southern South America, with two key genes (SP6A and IT1) from each parent driving tuber formation; domesticated ~7,000 years ago near Lake Titicaca, the potato is an evolutionary novelty that could inform modern breeding using wild relatives.













