Tag

Neuropathy

All articles tagged with #neuropathy

health-and-science1 month ago•4 min saved

Psilocybin Prevents Chemotherapy Nerve Damage in Mice

A study published in Science shows that psilocybin, the psychoactive compound in magic mushrooms, can prevent chemotherapy-induced peripheral neuropathy in mice. By activating specific receptors, psilocybin helps maintain mitochondrial transport in nerve endings, protecting them from damage caused by platinum-based drugs. This is the first evidence that a therapy can prevent this debilitating side effect, which affects up to 75% of cancer patients. Researchers at MD Anderson are launching a Phase 2 trial in November to test this approach in humans.

via Nature|

#cancer-research #chemotherapy #health-and-science

health1 month ago•96 min saved

Psilocybin May Shield Nerves From Chemotherapy Damage in Early Mouse Trials

A new study published in Science suggests that psilocybin may prevent chemotherapy-induced peripheral neuropathy (CIPN), a common side effect causing pain and numbness. In mouse trials, two doses of psilocybin before cisplatin treatment protected nerve endings by maintaining mitochondrial transport. Researchers plan a human trial involving 80 cancer patients starting in November 2026, with results expected in five years.

via Live Science|

#cancer-research #chemotherapy #clinical-trials

science7 months ago•7 min saved

Mitochondrial Rescue Points to Root Cause of Chronic Nerve Pain

Duke University researchers show that restoring healthy mitochondria to damaged nerve cells—via glia-to-neuron mitochondrial transfer or direct transplantation—reduces pain in models of diabetic and chemotherapy-induced neuropathy, suggesting cellular energy deficits underlie chronic nerve pain and offering a new treatment approach.

via SciTechDaily|

#glial-cells #mitochondria #mitochondrial-transfer

health9 months ago•4 min saved

Call for Stricter Regulations on Vitamin B6 Supplements Due to Neuropathy Risks

Australia is tightening regulations on vitamin B6 supplements due to reports linking high doses to neuropathy, with stricter rules and increased awareness needed globally, as high doses can cause significant nerve damage even from over-the-counter products.

via Medscape|

#health #hypervitaminosis #neuropathy

health1 year ago•0 min saved

Understanding Nerve Pain and Tingling in Hands and Feet

Experiencing pain or tingling in the hands or feet may indicate neuropathy, a condition involving nerve dysfunction in the limbs, according to expert Eva Feldman.

via The Washington Post|

#health #nerve-dysfunction #nerve-pain

health1 year ago•2 min saved

Effective Treatments for Reversing Neuropathy and Nerve Pain

The article discusses whether neuropathy, a condition characterized by nerve pain, can be reversed. It explores various treatments that may help alleviate symptoms, including medications, lifestyle changes, and alternative therapies. While complete reversal of neuropathy is challenging, these treatments can significantly ease nerve pain and improve quality of life.

via Woman's World|

#health #nerve-pain #neuropathy

health2 years ago•3 min saved

"Potential Link Between Daily Proton-Pump Inhibitor Use and Dementia/Neuropathy"

A retired individual with Barrett's esophagus and concerns about the effects of proton-pump inhibitors (PPIs) on dementia and neuropathy seeks advice from Dr. Keith Roach. While studies on the link between PPIs and atrial fibrillation (AFib) are inconclusive, the risk of esophageal cancer due to untreated acid reflux in Barrett's esophagus patients is a key concern. Dr. Roach recommends PPIs over H2 blockers for reducing the risk of esophageal cancer, despite known risks such as potential B12 deficiency and neuropathy. He emphasizes the importance of routine endoscopic surveillance and biopsies for early detection and treatment of any abnormal esophageal growth.

via OregonLive|

#barretts-esophagus #dementia #health

health-and-wellness2 years ago•2 min saved

"Dr. James Explains the Mystery Behind Burning Sensations in Feet"

Burning feet, often felt more acutely at night, can be caused by sensory neuropathy, where the sensory nerve fibers are disturbed. This condition can be associated with vitamin B deficiency, diabetes, or tibial tunnel syndrome. While there's no specific cure for the nerve dysfunction, treatments may include vitamin B supplements, blood-sugar-lowering drugs, physiotherapy, or surgery. Cooling the feet and certain medications like lidocaine, capsaicin, gabapentin, amitriptyline, and mexiletine can provide relief, although their effectiveness varies.

via The Telegraph|

##burningfeetsyndrome #diabetes

health2 years ago•2 min saved

COVID-19 Causes Unprecedented Vocal Cord Paralysis in Teenager

Doctors in Massachusetts have reported a case of a teenage girl whose vocal cords became paralyzed after contracting Covid-19. The girl required a tracheostomy for over a year to help her breathe, but the doctors were eventually able to remove it. While vocal cord paralysis has been linked to Covid-19 before, this is the first documented case in a teenager. The exact mechanism behind the paralysis is still unclear, but it is believed to be related to neuropathy caused by the virus. Doctors urge vigilance in considering vocal cord pathology as a potential complication in patients with voice, swallowing, or breathing issues after Covid-19 infection.

via Gizmodo|

#complications #covid-19 #health

health3 years ago•11 min saved

"Warning: Diabetic Foot Stages and Pedicure Risks Threaten Millions"

Diabetic foot problems, such as foot ulcers and neuropathy, are common complications of diabetes mellitus. These issues can arise due to nerve damage and poor blood flow, leading to open sores, infections, and changes in foot structure. Early symptoms include numbness, tingling, pain, dry skin, and changes in foot shape. Proper foot care, including wearing appropriate shoes, regular monitoring, and maintaining blood sugar levels, can help prevent complications. Treatment options range from wound dressings and antibiotics to surgery, depending on the severity of the condition. Regular foot checks and ongoing maintenance are crucial for healing and maintaining foot health in individuals with diabetes.

via Verywell Health|

#diabetes-mellitus #diabetic-foot #foot-care

health3 years ago•3 min saved

The Link Between Allergies, Sinus Pressure, and Headaches

A reader asks Dr. Keith Roach about histamine intolerance and its connection to high-histamine foods. Dr. Roach explains that there is no evidence of a deficiency in the enzymes that metabolize histamine and that treatment with diamine oxidase (DAO) has not been proven effective. Instead, he suggests trying newer antihistamines like cetirizine or fexofenadine, along with an H2 antihistamine like famotidine. Another approach is using Cromolyn before eating. In another question, Dr. Roach addresses numbness and burning in the outer thigh, which could be a result of nerve compression known as meralgia paresthetica. He recommends avoiding compression, and if necessary, seeking a nerve block or using medications for neuropathic pain.

via OregonLive|

#antihistamines #health #histamine-intolerance

medical-research3 years ago•0 min saved

"Breakthrough Research Offers Hope for Reversing Diabetic Neuropathy"

Researchers are conducting studies to reverse diabetic neuropathy, a common complication of diabetes that causes nerve damage and pain. The goal is to develop effective treatments that can alleviate symptoms and potentially reverse the condition, offering hope to millions of people living with diabetes.

via Daily Kos|

#diabetes #medical-research #neuropathy

health3 years ago•5 min saved

Understanding and Alleviating Numbness in Feet

Numbness in the feet can be a symptom of various medical conditions affecting the nervous or vascular systems, such as neuropathy or diabetes. It can also be caused by injuries or mental health conditions like anxiety. Home remedies like massage and compression socks can help alleviate symptoms, while treatment options may include medications, physical therapy, and surgery. Proper foot care and following healthcare provider's instructions are crucial for preventing complications, as chronic foot numbness can lead to foot ulcers and even amputation, particularly in cases of poorly controlled diabetes.

via Verywell Health|

#diabetes #feet #health

health3 years ago•4 min saved

Neuroinflammation: The Culprit Behind Alcohol-Induced Pain

Chronic alcohol consumption can increase sensitivity to pain through two distinct molecular mechanisms: one related to alcohol intake and the other to alcohol withdrawal. Researchers at Scripps Research have discovered that neuroinflammation plays a key role in the development of chronic alcohol-induced allodynia and neuropathy. The study highlights two different conditions of alcohol consumption: excessive drinkers who develop alcohol dependence and moderate drinkers who make daily recreational alcohol consumption. These two different conditions showed different types of pain: withdrawal hyperalgesia in excessive drinkers who develop dependence and alcohol neuropathy in 50 percent of moderate drinkers.

via PsyPost|

#alcohol #health #microglia

health-and-wellness3 years ago•6 min saved

"Recognizing Critical Neuropathy Symptoms"

Neuropathy is a catch-all term for damage to nerves that branch out from our brains and spinal cords to the rest of our bodies. Symptoms include tingling or pain in feet or hands, feeling weak or unsteady in feet and legs, muscle cramping or twitching, and abnormalities in pulse or blood pressure. Neuropathy can have many causes, can affect one nerve or many, and can have different treatments and varying outlooks. It’s important to get a diagnosis so you can get the right care. It is possible to reduce your risks for many common forms of neuropathy by eating healthy, exercising regularly, avoiding toxic chemicals, smoking and heavy alcohol use, as well as repetitive motions and cramped positions that put pressure on nerves.

via AARP|

#diabetes #health-and-wellness #neuropathy