Tag

Ovarian Cancer

All articles tagged with #ovarian cancer

health2 days ago•4 min saved

Outdated Genetic Tests May Leave Thousands of Women Unaware of Cancer Risks

Women who tested negative for cancer-related gene mutations in the 1990s and 2000s are now advised to retest due to significant advancements in genetic screening technology. Early tests focused only on BRCA1 and BRCA2 genes, but modern panels analyze dozens of additional genes linked to breast and ovarian cancer. A 2023 study found that 17.3% of individuals who initially tested negative were found to have a variant upon retesting. Experts warn that many patients remain unaware of this need, potentially delaying preventive measures. While barriers like cost and limited insurance coverage exist, retesting provides critical data for risk management and future medical decisions.

via The Washington Post|

#brca1 #breast-cancer #genetic-testing

biotech8 days ago•1 min saved

Genmab’s Rina-S Shows Superior Survival and Safety Profile vs. AbbVie’s Elahere

Genmab’s rinatabart sesutecan (Rina-S) demonstrated a median progression-free survival of 9.5 months in platinum-resistant ovarian cancer, significantly outperforming AbbVie’s Elahere at 5.6 months. While the objective response rate was 45.9%, analysts highlighted superior safety profiles, including no ocular toxicity, and potential for $2 billion in sales.

via Fierce Biotech|

#abbvie #antibody-drug-conjugate #biotech

health11 days ago•25 min saved

Why doctors are not yet routinely offering fallopian tube removal to prevent ovarian cancer

A new wave of medical guidance and clinical trials is pushing for wider adoption of risk-reducing salpingectomy, a procedure that removes fallopian tubes to prevent ovarian cancer. While evidence suggests this surgery can cut cancer risk by nearly 80%, it remains underutilized due to a lack of routine clinical counseling and patient awareness. Recent updates from the American College of Obstetricians and Gynecologists (ACOG) and new trials like the SOROCk study aim to bridge this gap by offering alternatives to immediate surgical menopause.

via The Washington Post|

#brca #health #ovarian-cancer

health14 days ago•7 min saved

Irregular Periods Led to Stage 1 Ovarian Cancer Diagnosis for Australian Papercrafter

Natalie May, an Australian papercraft expert, was diagnosed with stage 1 ovarian cancer at age 37 after noticing irregular bleeding. Her prompt medical response prevented the cancer from advancing to later stages. She now uses her platform to advocate for early symptom recognition, highlighting that ovarian cancer is increasingly affecting younger women.

via Business Insider|

#cancer-symptoms #early-detection #health

health24 days ago•5 min saved

Ovarian Cancer’s Silent Signs: Why Persistent Symptoms Demand Action

Ovarian cancer remains difficult to detect early due to vague symptoms and the lack of a reliable population-wide screening test. While often associated with older women, cases in younger individuals highlight the need for vigilance. Experts emphasize that persistent symptoms like bloating, pelvic pain, and urinary changes should not be dismissed, as early diagnosis significantly improves treatment outcomes.

via The Times of India|

#early-diagnosis #health #medical-screening

health27 days ago•257 min saved

47-Year-Old’s Sudden Stomachache Led to Ovarian Cancer Diagnosis, Highlighting Need for Symptom Awareness

A 47-year-old woman in New York was diagnosed with Stage 3 ovarian cancer after experiencing a sudden, severe stomachache that prompted an emergency room visit. Although ovarian cancer typically affects older women, this case highlights the importance of recognizing vague symptoms. Doctors emphasize that there is no routine screening for the disease, so women must monitor for persistent bloating, early satiety, abdominal pain, and toilet changes. The patient, who had no family history or genetic risk factors, is now cancer-free after surgery and chemotherapy.

via today.com|

#beat-acronym #early-detection #health

health28 days ago•22 min saved

New guidelines urge doctors to discuss fallopian tube removal for average-risk women

The American College of Obstetricians and Gynecologists has updated its guidelines to recommend that doctors discuss bilateral salpingectomy with women who have completed childbearing. This procedure, which removes the fallopian tubes, can reduce the risk of ovarian cancer by nearly 80%. The update aims to address the lack of effective screening for the disease, which remains the fifth-deadliest cancer among women in the U.S.

via The Washington Post|

#health #medical-guidelines #ovarian-cancer

health29 days ago•10 min saved

Minnesota survivor urges women to stop dismissing ovarian cancer symptoms as aging

Becky Drexler, a Minnesota woman diagnosed with stage 3B ovarian cancer in 2018, warns that vague symptoms like bloating and frequent urination are often mistaken for aging. Her story highlights the lack of reliable screening tools and the critical need for early detection, as advanced-stage diagnoses remain common.

via Fox News|

#advocacy #cancer-symptoms #early-detection

health1 month ago•7 min saved

Young Huddersfield mum urges vigilance for ovarian cancer

Alex Littlewood, 25, from Huddersfield, was diagnosed with incurable ovarian cancer shortly after giving birth and is urging other women to seek medical advice for persistent symptoms. The BEAT campaign highlights signs such as bloating, early fullness, abdominal pain, and changes in toilet habits, and experts emphasise that ovarian cancer can affect younger women as well, making early testing crucial.

via bbc.com|

#awareness #health #nhs

health1 month ago•10 min saved

Caernarfon teen's ovarian cancer triggers menopause and sparks a new purpose

A 19-year-old from Caernarfon, Enlli Thompson, was diagnosed with stage 3 ovarian cancer after years of misattributed symptoms; she had a hysterectomy that caused immediate menopause and ended her fertility, but she froze seven eggs before chemotherapy and is now navigating menopause while campaigning for awareness and pursuing a career in cancer care.

via BBC|

#fertility #health #menopause

science2 months ago•6 min saved

Sugary Signal: Fructose From Senescent Cancer Cells May Drive Ovarian Tumor Spread

A Nature Aging study shows fructose secreted by chemotherapy‑induced senescent ovarian cancer cells acts as a signaling molecule that reduces cell adhesion and promotes detachment and metastasis in cell cultures and mice; altering fructose metabolism blocked movement, and high-fructose intake worsened spread in animals, suggesting dietary fructose restriction and senolytic therapies could improve treatment outcomes—though findings are preclinical and not yet applicable to humans.

via ScienceAlert|

#cancer #fructose #metastasis

health2 months ago•8 min saved

Fructose as a Hidden Signal May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute found that fructose released by treatment-surviving ovarian cancer cells acts as a signal that weakens cell–cell adhesion and promotes detachment and spread. The effect can occur even without chemotherapy, and higher dietary fructose may influence tumor behavior, with cholesterol-lowering statins also weakening cancer cell adhesion. The study, published in Nature Aging, raises the possibility that this mechanism could occur in other torso-spreading cancers, though clinical studies are needed.

via SciTechDaily|

#chemotherapy #fructose #health

health-and-medicine2 months ago•8 min saved

Sweet Signal: Fructose Secreted by Chemo-Treated Cells May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute report that fructose released by chemotherapy-surviving ovarian cancer cells acts as a signal to neighboring tumor cells, promoting detachment and metastatic spread. In preclinical tests, high dietary fructose could enhance cancer spread by lowering cholesterol production in nearby cells, weakening cell adhesion; the finding also suggests interactions with cholesterol-lowering drugs (statins). While intriguing, these effects have not been tested in patients, and researchers caution against changing medications yet. More studies are planned to see if this pathway affects other cancers and whether diet or statin use could influence outcomes.

via ScienceDaily|

#chemotherapy #cholesterol #fructose

science2 months ago•12 min saved

Fructose may fuel cancer spread after chemotherapy, study suggests

A new study finds the sugar fructose produced by chemotherapy-surviving tumor cells can signal neighboring cancer cells to spread, potentially affecting ovarian cancer progression and raising questions about diet and statin interactions. The findings are preclinical and suggest nutrition could influence cancer progression, but more research is needed before changing patient care.

via The Independent|

#cancer #chemotherapy #fructose

business2 months ago•327 min saved

J&J eyes up to $5.5B to settle talcum-powder cancer lawsuits

Johnson & Johnson has set aside up to $5.5 billion to resolve about 76,000 US lawsuits alleging its talcum powder products caused ovarian cancer, offering plaintiffs up to $3 billion in 2027 with any remaining payouts after 2028; the deal would require acceptance by at least 95% of the claimants’ law firms to proceed. The company has faced decades of talc litigation, has defended the safety of its products, and has already shifted away from talc-based powder in North America (2020) and worldwide (2023).

via CNN|

#business #johnson-and-johnson #lawsuits