Tag

Ovarian Cancer

All articles tagged with #ovarian cancer

Switching From Talc Powders to Lower Cancer Risk, say Oncologists
health9 days ago

Switching From Talc Powders to Lower Cancer Risk, say Oncologists

Oncologists warn talc-based powders (used in baby and body powders) may carry cancer risk due to asbestos contamination in talc deposits; the World Health Organization classifies asbestos-contaminated talc as carcinogenic. While not all talc causes cancer, exposure from mining near asbestos raises concerns, so experts urge ditching talc-based powders and opting for safer alternatives like cornstarch, arrowroot, or rice starch; there is no known safe dose for talc-based powders.

Chris Evert Battles Cancer Again, Will Skip Wimbledon Coverage
sports19 days ago

Chris Evert Battles Cancer Again, Will Skip Wimbledon Coverage

Tennis legend Chris Evert revealed that her ovarian cancer has returned and she will undergo surgery and chemotherapy, forcing her to skip ESPN Wimbledon coverage and step back from professional duties to focus on treatment; she previously beat the disease in 2022 and 2023, and a Netflix documentary about her and Martina Navratilova's cancer battles is releasing.

Evert confronts a third ovarian cancer recurrence and starts chemotherapy
health19 days ago

Evert confronts a third ovarian cancer recurrence and starts chemotherapy

Tennis great Chris Evert, 71, announced that her ovarian cancer has returned for a third time after recent CT and PET scans. She has already undergone surgery and will begin chemotherapy in the coming weeks, stepping back from ESPN Wimbledon coverage to focus on treatment. Evert previously battled ovarian cancer in 2021 and 2023 and beat it both times; her news comes just as Netflix releases a documentary about her and Martina Navratilova, Chris & Martina: The Final Set.

Chris Evert's ovarian cancer returns; Wimbledon absence and chemotherapy ahead
sports19 days ago

Chris Evert's ovarian cancer returns; Wimbledon absence and chemotherapy ahead

Former Wimbledon champion Chris Evert, 71, says her ovarian cancer has returned for a third time. After CT and PET scans, she underwent surgery and will begin chemotherapy in the coming weeks, forcing her to miss Wimbledon and step back from broadcasting duties to focus on treatment; she remains optimistic and grateful for support as she fights the disease.

Postcode gap in BRCA testing could shape ovarian cancer risk in Wales
health29 days ago

Postcode gap in BRCA testing could shape ovarian cancer risk in Wales

A Welsh woman believes she might have avoided ovarian cancer if Wales had offered BRCA genetic testing in 2014 like England did for under-50 women with triple-negative breast cancer; she only discovered her BRCA1 mutation after an ovarian cancer diagnosis in 2021, highlighting cross-border and regional disparities in access to testing and screening that Wales says it is addressing in a new cancer plan.

Mom of three battles advanced ovarian cancer after doctors dismissed her symptoms as a hernia
health29 days ago

Mom of three battles advanced ovarian cancer after doctors dismissed her symptoms as a hernia

A mother of three endured years of dismissed symptoms before a female doctor finally recognised something was wrong and diagnosed Stage 4b low-grade serous ovarian cancer (LGSOC). She underwent extensive surgery and chemotherapy, later achieving remission and now campaigns to raise awareness of LGSOC and the dangers of dismissing women's health concerns, particularly around World Ovarian Cancer Day.

England approves first breakthrough ovarian cancer drug in over two decades
health1 month ago

England approves first breakthrough ovarian cancer drug in over two decades

NHS England has approved mirvetuximab soravtansine (Elahere) for FRα‑positive, platinum‑resistant epithelial ovarian, peritoneal or fallopian tube cancer, offering an option for hundreds of women each year and the first new drug for resistant ovarian cancer in over 20 years. The drug, given by IV every three weeks, delayed disease progression and extended median survival by about four months in a global trial, with a subset of patients showing tumor shrinkage and a tolerable safety profile. A new NICE approval, alongside a commercial arrangement with AbbVie, supports its use in NHS settings, potentially benefiting up to ~400 women annually in England.

αKG-driven carnitine synthesis promotes histone acetylation and DNA repair in HR-proficient cancers
science1 month ago

αKG-driven carnitine synthesis promotes histone acetylation and DNA repair in HR-proficient cancers

In homologous recombination–proficient cancers, α-ketoglutarate (αKG) fuels de novo carnitine synthesis via the enzyme TMLHE, boosting acetyl-CoA–dependent histone acetylation at site-specific marks (H3K23ac, H4K8ac, H4K12ac) and enabling HR repair; disrupting this αKG–carnitine axis sensitizes cells to DNA-damaging therapies, while providing αKG or acetylcarnitine rescues repair. Clinically, high TMLHE or acetylcarnitine correlates with worse progression-free survival in ovarian cancer patients treated with platinum chemotherapy. Pharmacologically inhibiting carnitine synthesis (mildronate) reduces tumor burden in combination with cisplatin in mice. These findings reveal a nonredundant nuclear acetyl-CoA pool provided by de novo carnitine synthesis that links metabolism to site-specific histone acetylation and HR proficiency, offering potential biomarkers and therapeutic strategies.

Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England
health2 months ago

Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England

England’s cancer data from 2001–2019 show rising cancer incidence among people under 50, with bowel and ovarian cancers increasing most notably. While obesity and certain behavioral factors contribute, they do not fully explain the trend, suggesting possible age-specific exposures or additional influences (reproductive history, early-life factors, diet, microbiome, and detection changes). The study is observational and cannot prove causation.

IVF and cancer risk: overall rates similar, but small increases for some cancers
health4 months ago

IVF and cancer risk: overall rates similar, but small increases for some cancers

A large Australian study of 417,984 women who received fertility treatments (IVF, insemination, or clomiphene citrate) found the overall cancer rate was similar to the general population. However, clomiphene citrate users had a 1.04× higher cancer rate (~8.6 extra cancers per 100,000 women per year), and rates of uterine cancer, ovarian cancer (except for clomiphene users), and melanoma were 1.07–1.83× higher. Conversely, cervical and lung cancers were 1.43–1.92× lower. The study cannot establish causation and likely reflects underlying risk factors (eg, endometriosis, ethnicity, smoking) and screening practices, with absolute cancer numbers remaining small. Routine cancer screening remains important for anyone undergoing fertility treatment.

Tribute to a fitness pioneer: Stephanie Buttermore dies at 36, fiancé confirms
health4 months ago

Tribute to a fitness pioneer: Stephanie Buttermore dies at 36, fiancé confirms

Fitness influencer and doctor Stephanie Buttermore has died at 36, as fiancé Jeff Nippard announced the death was sudden. She researched ovarian cancer and championed healthy weight gain and body positivity, notably through her All In challenge, and had stepped away from social media in 2024 for mental health; details about the cause of death were not released.

Influencer Stephanie Buttermore Dies at 35; Death Cause Not Disclosed
lifestyle4 months ago

Influencer Stephanie Buttermore Dies at 35; Death Cause Not Disclosed

Fitness influencer and scientist Stephanie Buttermore, longtime partner of Jeff Nippard, died at 35. A statement from Nippard’s team said she passed away but did not disclose a cause. Fans had noted her two-year social media absence; her last post in 2024 discussed anxiety and taking a break from social media. Her PhD research was in ovarian cancer, but no official reason for her death has been released.

Ombudsman links cancer patient’s death to NHS delays; Essex trust vows reforms
health6 months ago

Ombudsman links cancer patient’s death to NHS delays; Essex trust vows reforms

The Parliamentary and Health Service Ombudsman found delays of 49 days to diagnose and 81 days to start treatment for terminal ovarian cancer at Mid and South Essex NHS Foundation Trust, far exceeding targets, contributing to the patient’s death; the trust apologized and outlined reforms to speed waiting times.