Tag

Sperm

All articles tagged with #sperm

Air pollution may reprogram sperm DNA, raising fertility concerns
health15 days ago

Air pollution may reprogram sperm DNA, raising fertility concerns

A large fertility study following over 2,000 men links exposure to outdoor pollutants (notably ozone and nitrogen dioxide) during sperm development to subtle DNA methylation changes in sperm that regulate gene activity. Researchers identified 39 pollution-associated DNA changes, including in the GNAS gene, suggesting a potential mechanism by which air pollution could affect fertility. However, a direct link to infertility has not been proven, and further work is needed to confirm clinical significance.

GLP-1 Weight-Loss Drugs Show Potential to Improve Male Fertility, Study Finds
health1 month ago

GLP-1 Weight-Loss Drugs Show Potential to Improve Male Fertility, Study Finds

A UK study suggests GLP-1 weight-loss drugs (dulaglutide, liraglutide, semaglutide) may improve male fertility markers—boosting testosterone and sperm quality—primarily through weight loss. Liraglutide increased testosterone, LH and FSH and improved sperm parameters; semaglutide improved sperm morphology; dulaglutide showed no significant hormonal changes. Researchers caution that benefits appear indirect and larger studies are needed; GLP-1s should not be used specifically for fertility.

GLP-1 weight-loss drugs linked to improved male fertility in a 24-week study
health1 month ago

GLP-1 weight-loss drugs linked to improved male fertility in a 24-week study

A CNN Health summary reports that men aged 18–65 with high BMI who took GLP-1 medications (used for diabetes and weight loss) for 24 weeks showed higher testosterone, increased sperm count, and better sperm quality. While findings hint at fertility benefits and potential as an alternative to testosterone therapy, experts caution that more research is needed and results may not apply to all men. Benefits may stem from weight loss and reduced inflammation, but clinicians emphasize fertility evaluations and ongoing healthy lifestyle choices, as weight loss alone does not guarantee improved fertility.

Khloé Kardashian Secures Tristan Thompson's Embryos and Keeps His Sperm Banked
celebrity1 month ago

Khloé Kardashian Secures Tristan Thompson's Embryos and Keeps His Sperm Banked

Khloé Kardashian reveals on The Cut that Tristan Thompson signed over some of his frozen embryos to her after he had a vasectomy, effectively giving her ownership of his sperm; Thompson says he's done having kids unless they're from Kardashian's embryos, while Kardashian notes she’s preserving sperm for a future possibility, and the couple share two children, True and Tatum.

Cannabis use linked to lower sperm quality in men, experts say
health2 months ago

Cannabis use linked to lower sperm quality in men, experts say

Cannabis use, especially heavy and chronic use, may impair male fertility by lowering sperm count and mobility and altering reproductive hormones; human studies link cannabis to reduced semen quality, though evidence is mixed; experts say stopping cannabis for at least three months before attempting conception can improve fertility, highlighting that male infertility is common and under‑evaluated.

Chronic stress can quietly erode a man's fertility
health3 months ago

Chronic stress can quietly erode a man's fertility

Chronic stress can disrupt hormones and increase oxidative stress, which may lower sperm count, motility and morphology. Because sperm development takes 2–3 months, prolonged stress can affect future semen samples. It often coexists with poor sleep, weight gain and higher substance use, so fertility is usually multi-factorial. A semen analysis is a common first step; improving sleep (7–9 hours), regular activity, weight management, and reducing nicotine/alcohol can help, alongside medical evaluation for underlying issues.

Cosmic parenthood in doubt as space-like microgravity halves sperm navigation
science3 months ago

Cosmic parenthood in doubt as space-like microgravity halves sperm navigation

New microgravity experiments using a tiny obstacle course showed human and mouse sperm navigated about 50% less effectively in space-like conditions, resulting in roughly a 30% drop in fertilization. While some sperm still reach the egg and may form higher-quality embryos, embryo development in weightlessness could pose major challenges, suggesting space reproduction may be possible only for the fittest sperm and with careful embryo protection as NASA pursues Moon and Mars settlements.

Space Sperm Need Gravity to Find Their Way
science3 months ago

Space Sperm Need Gravity to Find Their Way

Adelaide University researchers tested human, mouse, and pig sperm in a device simulating microgravity, finding that sperm struggled to navigate a maze mimicking the female reproductive tract and showing about a 30% reduction in successful navigation under zero gravity, underscoring gravity as a key factor in early reproductive success during space conditions.

Frequent Ejaculation Linked to Healthier Sperm, Review Finds
health3 months ago

Frequent Ejaculation Linked to Healthier Sperm, Review Finds

A review of nearly 150 studies finds that regular ejaculation or sex can help sperm quality, while abstinence modestly degrades it via increased oxidative stress and DNA damage, reducing viability and motility in humans and other animals. A recent IVF trial suggested higher fertilization success when men ejaculate within 48 hours of sample collection, though the impact on natural fertility remains unclear. The findings could lead clinics to reassess abstinence guidelines and emphasize sperm quality alongside quantity, while general health benefits of regular sexual activity appear unaffected.

Sperm Lose Direction in Microgravity, Raising Spaceflight Reproduction Concerns
science3 months ago

Sperm Lose Direction in Microgravity, Raising Spaceflight Reproduction Concerns

Researchers used a 3D clinostat to simulate microgravity and tested human, pig, and mouse sperm in a channel resembling the female reproductive tract; they found a significant drop in the number of sperm reaching the egg under microgravity, not due to motor changes but impaired direction sensing; fertilization dropped about 30% after four hours of exposure, with longer exposure causing delays and fewer embryos; progesterone could still guide sperm, indicating chemotaxis remains important; the findings, published in Communications Biology, imply spaceflight could affect reproductive outcomes in humans and livestock, highlighting the need for further research.

Sperm Lose Direction in Microgravity, Prompting Space Reproduction Research
space3 months ago

Sperm Lose Direction in Microgravity, Prompting Space Reproduction Research

Australian researchers used a clinostat to simulate microgravity and found human, mouse, and pig sperm become disoriented, with about a 40% drop in those reaching a simulated egg; microgravity also affected early embryo development in animals, though healthy embryos could form, and progesterone helped guide sperm. The findings underscore the importance of understanding reproduction in space for future Moon/Mars settlements and ongoing space biology programs, while noting radiation and ethical considerations remain challenges.

Frequent ejaculation linked to a small fertility boost, study finds
health3 months ago

Frequent ejaculation linked to a small fertility boost, study finds

A large meta-analysis across human and non-human studies shows that regular ejaculation helps prevent rapid deterioration of stored sperm, with longer abstinence associated with increased DNA damage and reduced motility. The findings suggest a modest fertility benefit from frequent ejaculation and hint that ejaculation timing could influence IVF success; current guidelines allowing up to seven days between samples may warrant revision.

Sperm RNA Clock Reveals Mid-Life Aging Cliff Linked to Child Health
science6 months ago

Sperm RNA Clock Reveals Mid-Life Aging Cliff Linked to Child Health

A new EMBO Journal study reports a mid-life, abrupt shift in sperm RNA—an “aging cliff”—that could influence what fathers pass to their offspring, offering a mechanism beyond DNA mutations that may help explain increased risks of neurodevelopmental and metabolic issues in children of older dads and supporting aging-related cautions in assisted reproduction.