Tag

Lifespan

All articles tagged with #lifespan

science5 days ago•37 min saved

Genes May Set Half Your Lifespan, New Study Finds

New research suggests genetic factors account for about 50% (roughly 50–55%) of human lifespan, higher than previous estimates. Using twin simulations and real-world data, researchers show that extrinsic mortality and historical age cutoffs biased earlier heritability estimates downward; when corrected, heritability rises to about half. Scandinavian twin data and studies of siblings of centenarians corroborate the finding, pointing aging research toward identifying the specific genetic variants that govern longevity.

via Yahoo News Canada|

#aging #genetics #heredity

health27 days ago•12 min saved

Brain Health Is a Lifespan Blueprint: Sleep, Gut, and Social Context Shape Aging

A new American Heart Association scientific statement argues that brain health is built across the entire life span, with external factors such as sleep quality, mental health, the gut microbiome, obesity, and social/environmental conditions strongly influencing the risk of stroke, cognitive decline, and dementia. Early adversity and chronic inflammation can echo into late life, but interventions at any age—like better sleep, stress management, Mediterranean-style eating, physical activity, and robust social connections—can bend the aging curve. The report calls for prevention, early detection, and policies to promote brain health from before birth through adulthood, supported by new research funding initiatives.

via Neuroscience News|

#brain-health #gut-brain-axis #health

animals1 month ago•20 min saved

Midlife Habits in a Tiny Fish May Forecast Lifespan Across Vertebrates

Stanford researchers tracked 81 African turquoise killifish with automated surveillance and found that midlife differences in sleep timing and daytime activity already distinguish longer‑ from shorter‑lived individuals. Using machine learning, just a few days of middle‑aged behavior could predict ultimate lifespan, revealing a stepwise aging pattern and linking behavioral changes to liver‑gene activity. The findings suggest wearable‑type monitoring in humans could detect early aging signals and guide preventive interventions in the future.

via Earth.com|

#aging #animals #behavior

science1 month ago•42 min saved

Earth Hits Halfway Mark of Its 4.5 Billion-Year Lifespan

New climate simulations suggest Earth is roughly halfway through its habitable lifetime, with about a billion years of livable conditions remaining before a runaway greenhouse vaporizes the oceans; after that, the Sun is expected to expand into a red giant around five billion years from now, likely ending Earth’s existence.

via Yahoo|

#earth #habitable-window #lifespan

science2 months ago•6 min saved

Lifespan Atlas Maps How Brain Networks Evolve Across Life

Researchers publish the first lifespan atlas of brain functional connectivity, using fMRI data from about 3,600 people aged from infancy to 100 years to chart how brain networks reorganize from sensory processing to higher‑order cognition and relate to cognitive performance in young adults.

via Nature|

#brain #fmri #functional-connectivity

neuroscience2 months ago•80 min saved

Three Gradients Shape Lifespan Cortical Hierarchy

A large-scale lifespan study maps three core functional gradients—sensory–association (SA), visual–somatosensory (VS), and modulation–representation (MR)—across birth to 100 years, showing early anchoring to primary sensory systems, differentiation along association and control axes through development, and later dedifferentiation with aging; these gradients relate to cognitive performance, structure–function coupling, and transcriptomic patterns, providing a normative lifespan atlas for brain organization.

via Nature|

#brain-development #fmri #functional-gradients

health2 months ago•4 min saved

The motherhood sweet spot: two to three kids linked to longer life

A Finnish twin study of almost 15,000 women found that having about two to three children is associated with the slowest aging and longest life, while having far more (around 6.8) or not having children is linked to higher mortality and faster biological aging; age at childbirth also matters, with earlier births tied to faster aging. The findings show associations, not causation, and researchers caution against changing personal reproductive plans based on this study, noting that many factors influence aging and lifespan.

via New York Post|

#aging #birth #health

health2 months ago•12 min saved

Anxiety Across the Lifespan: Practical Steps to Cope at Any Age

A life-span feature shows anxiety as a common, normal response to uncertainty that spans childhood to older age, offering stage-specific strategies: validate and normalize feelings in kids, model openness for teens, foster healthy habits and social connection in young adulthood, prioritize friendship and self-care in midlife, and use CBT, sleep hygiene and gradual exposure in older age, with guidance on when to seek help.

via The Guardian|

#anxiety #cbt #coping-strategies

science2 months ago•7 min saved

Genes Take the Lead on Longevity, Twin Study Shows

A twin-registry analysis that accounts for extrinsic mortality finds genetics account for about 50% of variation in human lifespan, more than double previous estimates, reshaping how scientists study aging and search for longevity genes.

via SciTechDaily|

#aging #genetics #heritability

science2 months ago•10 min saved

Aging in Steps: Behavior Predicts Lifespan in Killifish

Researchers monitored 81 African turquoise killifish from adolescence to death, identifying 100 behavioral building blocks and showing that by early adulthood, differences in sleep and movement predict total lifespan. Shorter-lived fish nap more during the day and swim slower, while longer-lived fish stay active during daylight. Aging appears as 2–6 rapid transitions rather than a smooth decline, with coordinated changes in liver gene activity related to protein production and cellular maintenance aligning with the predictive behavioral shifts. The work suggests behavior can be a sensitive, noninvasive readout of aging and hints wearables could reveal human aging trajectories and potential intervention windows.

via Neuroscience News|

#aging #behavior #killifish

science2 months ago•5 min saved

Active days, longer life: a fish’s behavioural clock predicts lifespan

Scientists tracked 81 African turquoise killifish from adolescence to death with 24/7 video and a machine-learning model, finding that more active, faster-moving fish tended to live longer and those that slept mainly at night also reached older ages, while daytime napping correlated with shorter lifespans. The study suggests early-life behaviour can forecast ageing long before disease signs emerge.

via Nature|

#ageing #animal-behaviour #killifish

science2 months ago•20 min saved

Twin data suggests genetics plays bigger role in lifespan than previously thought

Using decades of twin data from Denmark and Sweden, researchers estimate that genetics account for about 55% of lifespan variation after removing extrinsic causes of death, with lifestyle and environment making up the remaining ~45%. The findings imply a possible genetic ceiling to human lifespan, though no single longevity gene exists and lifestyle still matters. The study calls for larger, more diverse datasets to confirm whether this genetic limit holds across populations.

via Earth.com|

#aging #genetics #heredity

science2 months ago•4 min saved

Birth Count May Echo in the Body's Clock, Finnish Study Finds

A Finnish study of 14,836 twin-derived women links both no children and high child counts (average ~6.8) to worse biological aging and higher mortality, while having about two to three children (and pregnancies at ages ~24–38) shows the best aging markers. Early births may also relate to aging, but effects largely fade after accounting for lifestyle factors. The findings are observational and not causal, and unmeasured variables may influence both reproductive history and health; researchers caution against using this to guide individual family planning.

via ScienceAlert|

#aging #biological-aging #evolutionary-biology

health-and-medicine2 months ago•5 min saved

High tyrosine linked to shorter lifespans in men, large study suggests

A UK Biobank study of more than 270,000 participants found higher blood tyrosine levels linked to shorter life expectancy in men—potentially shaving nearly a year off lifespan—with no clear effect in women. After adjusting for related amino acids and factors, phenylalanine showed no association. Possible explanations include insulin resistance and sex-specific hormone pathways; the study does not test tyrosine supplements directly, but results suggest dietary protein or tyrosine levels could influence aging, warranting further research.

via ScienceDaily|

#amino-acids #health-and-medicine #lifespan

science3 months ago•17 min saved

Common high-blood-pressure drug hints at anti-aging potential in animals

A long-used hypertension medication, rilmenidine, extended lifespan in the worm C. elegans and induced youthful metabolic changes in mice, pointing to aging pathways that can be slowed with an existing drug. The study links the effect to the nish-1 receptor and autophagy, with older animals benefiting nearly as much as younger ones, and suggests early human trials could focus on biomarkers if safety remains favorable.

via Earth.com|

#aging #aging-research #caloric-restriction-mimetics