Tag

Metabolic Disease

All articles tagged with #metabolic disease

archaeology27 days ago•44 min saved

Neanderthal Baby Growth Parallels Modern Humans, with Early Metabolic Clues

High‑resolution micro-CT analysis of three juvenile Neanderthal remains from Sesselfelsgrotte (about 90,000–50,000 years old) shows bone growth patterns akin to modern human fetuses, including prenatal development around eight to nine months of gestation, with long bones developing faster than the jaw. The teeth reveal interglobular dentine defects indicating metabolic stress during late pregnancy to early childhood, potentially vitamin/metabolism-related deficiencies, representing the oldest evidence of metabolic bone disease in a non-modern human lineage.

via Archaeology News Online Magazine|

#archaeology #early-childhood #growth

health1 month ago•29 min saved

Preconception health of fathers may influence future generations, study finds

A Washington State University study suggests a father’s health before conception can shape the future health of his children. Researchers found that the heritable information related to a father’s metabolic state is set early during sperm development in the testis, not primarily via mature sperm mitochondria. Using intracytoplasmic sperm injection (ICSI), they showed testis-derived sperm can transmit diet-related metabolic traits to offspring, indicating an early-development basis for this transmission. While these findings do not doom children to metabolic disease, they highlight a potential biological pathway and imply that improving paternal health before conception could benefit both fathers and their future children as part of a broader focus on paternal reproductive health.

via KOMO|

#health #intracytoplasmic-sperm-injection #metabolic-disease

health8 months ago•5 min saved

New Gut Hormone Found to Boost Fat Burning, Potentially Leading to Next Ozempic

Scientists discovered that the gut hormone FGF19 signals the brain to increase energy expenditure and fat burning, offering promising new avenues for obesity and metabolic disease treatments, similar to drugs like Ozempic.

via SciTechDaily|

#brain-signaling #fgf19 #health

health10 months ago•2 min saved

Vitamin's Potential to Reverse Common Liver Disease

Researchers discovered that microRNA-93 promotes fatty liver disease by inhibiting SIRT1, but vitamin B3 (niacin) can suppress miR-93, offering a promising, already-approved treatment pathway for MASLD, a common liver condition affecting 30% of the global population.

via SciTechDaily|

#fatty-liver-disease #health #metabolic-disease

health10 months ago•2 min saved

Gene Editing Boosts Baby's Health in Clinical Trial

Scientists used CRISPR-based base editing delivered via lipid nanoparticles to successfully treat a baby with a rare genetic metabolic disorder, marking a significant advancement in personalized gene therapy.

via Nature|

#baby #crispr #gene-editing

health11 months ago•2 min saved

Novo Nordisk's Wegovy Gains US Approval for MASH Treatment

Novo Nordisk's Wegovy has received accelerated FDA approval to treat MASH, making it the first GLP-1 therapy approved for this liver condition, based on promising early trial results, with plans for approval in Europe and Japan.

via Reuters|

#fda-approval #health #mash

health1 year ago•5 min saved

Surge in Severe Childhood Obesity and Declining Youth Health in America

A study finds that the percentage of children with 'extremely severe' obesity in the U.S. has more than tripled over 15 years, leading to higher risks of serious health problems like fatty liver and diabetes, highlighting a growing public health emergency and the need for better treatment access.

via Gizmodo|

#children #health #metabolic-disease

health-and-wellness2 years ago•4 min saved

"Uncovering the Hidden Weight Loss System Within Your Body"

Weight loss and diabetes drugs like Wegovy, Ozempic, and Mounjaro target regulatory pathways involved in obesity and diabetes, mimicking natural gut hormones produced in response to nutrients in food and influenced by the gut microbiome. While these drugs have shown effectiveness in weight loss and blood sugar control, they come with gastrointestinal side effects and potential long-term implications. Despite their promise, a healthy lifestyle involving whole foods, exercise, stress management, and sleep remains crucial for managing metabolic disease and overall health, particularly for those without obesity or diabetes.

via ScienceAlert|

#gastrointestinal-health #gut-microbiome #health-and-wellness

health2 years ago•4 min saved

"Uncovering the Natural Weight Loss System Within Your Body: The Role of Food and Gut Microbiome"

Incretin hormones, naturally produced in the gut, regulate metabolism and appetite, with the gut microbiome playing a crucial role. Drugs like Wegovy and Ozempic mimic these hormones, showing effectiveness in weight loss and blood sugar control. However, lifestyle factors such as diet and exercise remain important for managing metabolic disease. Reintroducing whole foods and promoting gut microbiome health may be key in addressing the root causes of obesity and diabetes.

via The Conversation|

#gut-microbiome #health #incretin-hormones

health2 years ago•2 min saved

"Breakthrough Discovery: AHA Identifies Multi-Organ Afflicting Heart Syndrome"

The American Heart Association has announced a new condition called Cardiovascular-Kidney-Metabolic Syndrome (CKM), which affects multiple organs in the body. CKM reflects the strong link between obesity, heart disease, diabetes, and kidney disease. There are four stages of CKM, with the highest risk for those who are obese or overweight. Prevention measures include maintaining a healthy weight, eating fresh foods, and engaging in physical activity. Medical experts aim to identify health factors impacting obesity and continue educating the public on health habits and preventative measures.

via KOMU 8|

#health #heart-disease #kidney-disease

health2 years ago•2 min saved

Snacking Sabotages Healthy Eating Habits for 25% of Individuals, Study Finds

A new study reveals that 1 in 4 people who eat healthy meals tend to undermine their efforts by consuming unhealthy snacks, such as ultraprocessed and sugary treats. The research emphasizes the importance of swapping unhealthy snacks for healthier options like fruit and nuts, as snacks account for nearly a quarter of our daily calorie intake. Snacking on highly processed foods and sugary treats can lead to increased hunger and negative health outcomes, including higher BMI, visceral fat mass, and triglyceride concentrations associated with metabolic diseases. The study also highlights the significance of snack timing, with late-night snacking linked to consuming calorie-dense foods high in fat and sugar. However, participants who frequently consumed high-quality snacks like nuts and fresh fruit were more likely to maintain a healthy weight. Experts recommend carrying convenient, nutritious snacks to maintain control over food choices and promote healthier snacking habits.

via CNN|

#health #healthy-eating #metabolic-disease

health3 years ago•2 min saved

Exploring the Link Between Genetics and Depression in Women.

A new study from McGill University has found that there are differences between male and female genes and how they relate to depression. Researchers identified 11 areas of DNA that were linked to depression in women and one in males. They also found depression was associated with metabolic disease in women, providing an important new aspect to consider when treating depressive symptoms. Despite the biological processes involved in depression being similar in males and females, researchers found that different genes were involved for each sex. This information can be useful to identify future sex-specific treatments for depression.

via Neuroscience News|

#depression #genetics #health