Tag

Preclinical Studies

All articles tagged with #preclinical studies

Ketogenic Diet Could Shield the Brain From Neurodegenerative Diseases, Review Finds
science2 days ago

Ketogenic Diet Could Shield the Brain From Neurodegenerative Diseases, Review Finds

A new review finds the ketogenic (keto) diet could offer neuroprotection against diseases like Alzheimer's, Parkinson's, and Huntington's by altering energy metabolism and increasing ketone use, which may reduce inflammation, boost autophagy, and improve gut-brain health; though most supporting studies are in animals, long-term safety, practicality, and clinical efficacy in people remain uncertain, and more trials are needed.

"Unlocking the Secrets of Longevity: From Cold Showers to Healthspan Restoration"
health-and-science2 years ago

"Unlocking the Secrets of Longevity: From Cold Showers to Healthspan Restoration"

Life Biosciences is focused on targeting the underlying biology of ageing to restore and prolong healthspan, defined as the number of healthy years lived. By addressing biological mechanisms of ageing, such as epigenetic modifications, the company aims to develop therapeutics that can reverse ageing and treat age-related diseases. Their lead program utilizes partial epigenetic reprogramming to treat age-related optic neuropathies, with plans to initiate human clinical trials in 2025. Additionally, they are exploring the potential of cellular rejuvenation in treating neurodegenerative diseases and other age-related conditions.