
25,000-Year-Old Betel Nut Use Reveals Ancient Psychoactive Habit
Scientists analyzing two 25,000–16,000 year-old skeletons from Sulawesi found abnormal tooth wear and chemical traces of arecoline, indicating betel nut chewing as far back as 25,000 years ago—well before agriculture—suggesting ancient people used the psychoactive substance (and possibly for pain relief) long before farming.













