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Oxidative Stress

All articles tagged with #oxidative stress

Spinach-Inspired Photosynthesis Targets Dry Eye in Eye Cells
science7 days ago

Spinach-Inspired Photosynthesis Targets Dry Eye in Eye Cells

Scientists at NUS bioengineered spinach-derived photosynthetic machinery to function in mammalian corneal cells via eye drops, using light to generate anti-inflammatory chemicals and combat oxidative stress in dry eye disease, a condition affecting about 1.5 billion people; the work, published in Cell, explores a novel, plant-based approach to treating dry eye by harnessing light-driven chemistry in eye tissues (still at early model stages).

via ZME Science|
#bioengineering#cornea#dry-eye-disease
Systemic racism-linked stress may drive higher pregnancy risks for Black women
health26 days ago

Systemic racism-linked stress may drive higher pregnancy risks for Black women

A review of 44 studies finds Black women have higher oxidative stress, inflammation, and uteroplacental vascular resistance during pregnancy, likely driven by socioenvironmental stressors such as systemic racism and deprivation rather than genetics, which may contribute to worse outcomes and higher maternal mortality in the UK. The researchers call for addressing root causes and increasing maternity-care investment.

via The Guardian|
#health#health-disparities#obstetrics
Frequent Ejaculation Linked to Healthier Sperm, Review Finds
health2 months ago

Frequent Ejaculation Linked to Healthier Sperm, Review Finds

A review of nearly 150 studies finds that regular ejaculation or sex can help sperm quality, while abstinence modestly degrades it via increased oxidative stress and DNA damage, reducing viability and motility in humans and other animals. A recent IVF trial suggested higher fertilization success when men ejaculate within 48 hours of sample collection, though the impact on natural fertility remains unclear. The findings could lead clinics to reassess abstinence guidelines and emphasize sperm quality alongside quantity, while general health benefits of regular sexual activity appear unaffected.

via gizmodo.com|
#abstinence#fertility#health
Centenarian Blood Reveals a 37-Protein Blueprint for Slower Aging
science2 months ago

Centenarian Blood Reveals a 37-Protein Blueprint for Slower Aging

Swiss researchers comparing blood from ages 30–60, 80–90, and 100+ found 37 proteins (about 5% of the 700+ measured) in centenarians that resemble the young group more than octogenarians, suggesting key aging mechanisms can be slowed. These proteins affect immunity, metabolism, red blood cell recycling, extracellular matrix maintenance, and oxidative stress, aligning with inflammaging and underscoring lifestyle factors—nutrition, exercise, and social connections—as actionable ways to promote healthy aging. Published in Aging Cell.

via ScienceAlert|
#aging#centenarians#longevity
Ultra-long runs may speed up red blood cell aging, study finds
science3 months ago

Ultra-long runs may speed up red blood cell aging, study finds

A study of 23 runners found that very long-distance races can injure red blood cells, reducing their flexibility and accelerating aging due to inflammation and oxidative stress, with longer races like the UTMB causing more damage; researchers caution the small sample size and call for more research into training and recovery strategies to minimize cellular damage.

via Runner's World|
#endurance-running#inflammation#oxidative-stress
Extreme Endurance Running Might Accelerate Red Blood Cell Aging
health3 months ago

Extreme Endurance Running Might Accelerate Red Blood Cell Aging

A study in Blood Red Cells & Iron finds ultramarathon races can damage red blood cells, making them less flexible due to mechanical stress and inflammation/oxidative stress; signs of accelerated aging appear after 40‑km races and worsen after 171‑km events, though long‑term effects and duration of damage are unclear; findings could influence training, recovery, and blood storage research, but the study has a small sample size and limited sampling points.

via SciTechDaily|
#aging#health#inflammation
Erythritol May Undermine Brain Shield, Raise Stroke Risk
science3 months ago

Erythritol May Undermine Brain Shield, Raise Stroke Risk

New lab and observational evidence suggests the sugar substitute erythritol can damage cells of the blood-brain barrier, trigger oxidative stress, and lower nitric oxide while raising endothelin-1, potentially narrowing cerebral vessels and hindering clot dissolution—factors that could elevate stroke risk; these findings align with studies linking erythritol to higher cardiovascular events, though most experiments used isolated cells and require validation in more realistic models.

via ScienceAlert|
#blood-brain-barrier#cardiovascular-health#erythritol
Scientists uncover the cause of 'old people' smell and how to eliminate it
health8 months ago

Scientists uncover the cause of 'old people' smell and how to eliminate it

Research reveals that the distinct 'old people smell' is caused by increased levels of the chemical 2-nonenal, which results from oxidative stress breaking down skin fats. Consuming mushrooms, rich in antioxidants like ergothioneine and spermidine, can help reduce this odor by neutralizing 2-nonenal, as traditional methods like showering and perfume are ineffective.

via Daily Express|
#2-nonenal#dietary-change#health
Daily Almond Consumption May Boost Health and Protect DNA
health9 months ago

Daily Almond Consumption May Boost Health and Protect DNA

Eating about 22 almonds a day may help reduce oxidative stress and improve overall oxidative health, potentially extending health span, according to a systematic review of multiple studies. Almonds are rich in antioxidants like vitamin E and polyphenols, which combat cellular damage, and incorporating them into the diet can be a proactive, low-risk strategy for disease prevention. However, due to their calorie content, almonds should replace other snacks rather than be added on top of a normal diet.

via MedicalNewsToday|
#almonds#antioxidants#health