
GLP-1 meds and Yom Kippur fasting: practical safety guidance
People taking GLP-1 medications (e.g., Ozempic, Mounjaro, Wegovy, Zepbound) can usually fast for Yom Kippur, but should plan with a clinician. For weekly injections, keep to the schedule; daily regimens may require timing adjustments, and oral GLP-1 pills are taken on an empty stomach, which may conflict with fasting. Those with diabetes face higher risks of lows when GLP-1s are used with other glucose-lowering drugs like insulin or sulfonylureas, so dosing and timing should be discussed with a doctor. Prefast meals, hydration, and blood-sugar monitoring are important; break the fast with a gentle, balanced meal and quick carbohydrates if needed. Seek medical guidance before fasting, especially if diabetes is not well controlled or if kidney issues or GI side effects are present.











