Tag

Spinal Cord Injury

All articles tagged with #spinal cord injury

science1 hour ago•5 min saved

Bidirectional brain implant restores hand movement and touch in quadriplegia

A single paralysed patient with quadriplegia regained voluntary hand movement and partial touch using a bidirectional brain-computer interface: implanted brain microelectrodes plus skin-stimulation patches translated his intended movements into nerve stimulation, with sensors providing touch feedback. Over 35 weeks he showed substantial arm-strength gains (87% in one measure reported as 86%/62% in the study) and could perform tasks like feeding himself and wiping his mouth; the work, published in Nature Medicine, marks a significant advance in neuroprosthetics but remains preliminary with one participant.

via Financial Times|

#brain-computer-interface #medical-science #neuroprosthetics

science1 month ago•41 min saved

Magnetic NPC Bots Repair Severed Spinal Cords in Mice, Hinting at a Breakthrough Therapy

ETH Zurich researchers engineered NPCbots—magnetically guided nanoparticles paired with patient-derived neural progenitor cells—to bridge a completely severed spinal cord in mice (and showed promising results in zebrafish). After 28 days, nerve ends reconnected and gait and coordination improved, with no adverse effects, signaling a potential new therapy for spinal injuries pending further animal testing and optimization of magnetic stimulation before human trials.

via Good News Network|

#medicine #nanotechnology #neuroscience

health2 months ago•6 min saved

NG101 Antibody Clears Growth Barrier to Boost Spinal Cord Repair

In a multicenter phase 2b trial, NG101 neutralizes Nogo-A, enabling surviving and newly grown nerve fibers to regenerate around spinal lesions and reestablish connections with the spinal centers that control the limbs. MRI data show faster lesion reduction and preserved tissue, providing objective biomarkers for early treatment effects and suggesting potential gains in hand/arm function after acute cervical spinal cord injury, though full mobility restoration remains uncertain.

via Neuroscience News|

#health #mri #nerve-regeneration

health4 months ago•5 min saved

Paralysis Allegations Shake Nura Pain Clinic Over Spinal Stimulators

Three patients allege that spinal cord stimulator implants at Nura Pain Clinic caused paralysis or serious injuries, leading to lawsuits accusing doctors of risky placement and inadequate warnings; a third patient has joined the suits as the clinic says it emphasizes informed consent while litigation unfolds, and FDA data show thousands of adverse events linked to these devices, including cases of paralysis.

via kare11.com|

#adverse-events #health #lawsuit

science5 months ago•4 min saved

Dancing molecules drive repair in lab-grown human spinal cords

Northwestern researchers grew 3-millimeter-wide human spinal cord organoids from iPSCs, injured them in two ways, and treated them with IKVAV-PA 'dancing' supramolecular peptides that form a scaffold and promote axon regrowth. The treated tissues showed reduced glial scar and inflammation and enhanced neurite growth, aligning with prior mouse data and suggesting potential for human therapies—though clinical use is years away. The work was published in Nature Biomedical Engineering.

via ScienceAlert|

#axon-regeneration #dancing-molecules #glial-scar

science6 months ago•5 min saved

New Brain Cell Discovery Could Revolutionize Spinal Cord Injury Treatment

Scientists at Cedars-Sinai discovered a new role for astrocytes, called lesion-remote astrocytes (LRAs), which communicate with immune cells to clear debris and promote repair in spinal cord injuries, potentially leading to new treatments for neurological diseases.

via SciTechDaily|

#astrocytes #brain-injury #immune-signaling

health6 months ago•3 min saved

Aging Alters Spinal Cord Injury Recovery Unexpectedly

A study published in Neurology found that while neurological recovery after spinal cord injury is similar across ages, older adults, especially those over 70, experience significantly less improvement in daily functioning and mobility, highlighting the need for age-specific rehabilitation approaches.

via SciTechDaily|

#aging #functional-abilities #health

science-and-technology6 months ago•3 min saved

First Wheelchair User Launches to Space on Blue Origin Mission

Michaela Benthaus, a German aerospace engineer and wheelchair user, became the first person with a disability to travel past the Kármán Line aboard a Blue Origin New Shepard capsule, experiencing microgravity and inspiring others with her journey.

via CNN|

#blue-origin #microgravity #science-and-technology

health8 months ago•1 min saved

Pennsylvania Man Walks Again After Experimental Drug Trial

A Pennsylvania man with a spinal cord injury has experienced significant improvement in mobility after receiving an experimental drug in a clinical trial, raising hope for future treatments for similar injuries.

via CBS News|

#clinical-trial #experimental-drug #health

health8 months ago•2 min saved

Scientists Discover Old Drug Thiorphan as Potential Spinal Cord Regeneration Therapy

Researchers at UCSD have identified the existing drug Thiorphan as a potential treatment to regenerate nerve cells in the spinal cord, showing promising results in animal models and human neuron studies, which could lead to new therapies for paralysis in the future.

via Times of India|

#drug-repurposing #health #neuroregeneration

medical-research8 months ago•28 min saved

Bioinformatics Accelerates Development of Regenerative Therapies for Spinal Cord Injury

Researchers identified thiorphan as a promising drug to promote neural regeneration and functional recovery after spinal cord injury by using a bioinformatics-driven pipeline, in vitro and in vivo testing, and validation in primate and human neurons, showing its potential for clinical translation.

via Nature|

#drug-discovery #medical-research #neural-repair

obituary8 months ago•3 min saved

Obituary for Thomas (Tom) Charles Perley

Thomas (Tom) Charles Perley, a bright and independent man with Asperger’s Syndrome, passed away at 58 due to complications from a spinal cord injury sustained in a car accident. He was known for his intelligence, love of travel, music, and humor, and he cherished his independence and community involvement. His life was celebrated in a memorial service in Portland, Maine, and donations in his memory support Camp Nuhop and rehabilitation services.

via Wooster Daily Record|

#autism-spectrum #celebration-of-life #independent-living

local-news9 months ago•5 min saved

Rexburg 4-Year-Old Faces Paralyzing Crash After Infant Recovery

Four-year-old Carter Grover, who previously recovered from infant paralysis caused by transverse myelitis, is now paralyzed from the neck down after a severe car crash that injured his spinal cord. Despite grim medical prognoses, his family and community are rallying to support his recovery and care, highlighting his resilience and the family's strength.

via KSL.com|

#car-crash #carter-grover #community-support

medicine10 months ago•104 min saved

Advances in Blood Pressure Regulation Post-Spinal Cord Injury Using ONWARD ARC-IM Therapy

The article investigates the neuronal basis of autonomic dysreflexia after spinal cord injury, identifying specific neuronal subpopulations and their reorganization that trigger this life-threatening condition, and explores therapeutic strategies like electrical stimulation to modulate these neural circuits.

via Nature|

#autonomic-dysreflexia #medicine #neuronal-architecture

health10 months ago•1 min saved

Brazil Unveils Revolutionary Drug to Reverse Spinal Cord Injuries in São Paulo

Brazilian researcher Tatiana Coelho de Sampaio and her team have developed polylaminin, a groundbreaking drug derived from placental protein, which has shown promise in regenerating the spinal cord and restoring movement in patients with paralysis, with successful experimental results and no reported side effects.

via Folha de S.Paulo|

#brazil #drug-development #health