Tag

Microbiome

All articles tagged with #microbiome

science2 days ago•50 min saved

Ancient gut microbes traveled with humans from Africa to the Americas, study finds

A new study in Nature reveals that many gut bacteria co-migrated with humans out of Africa and into the Americas tens of thousands of years ago. Researchers compared the microbiomes of the Tsimane people in Bolivia and the Hadza in Tanzania, finding 1,231 shared microbial species. Most of these species are rare or absent in industrialized populations, suggesting a long-term co-evolution that is now being disrupted by modern lifestyles.

via Nature|

#anthropology #genetics #human-evolution

health6 days ago•29 min saved

Sugar intake during antibiotic use accelerates gut microbiome collapse

A new study in Nature reveals that consuming sugary foods while taking antibiotics significantly worsens gut microbiome disruption. Researchers found that sugar intake during antibiotic treatment led to a 24% drop in bacterial diversity for every 100-gram increase in sweets, promoting the overgrowth of harmful Enterococcus bacteria. This effect was confirmed in mouse models, where sugar supplementation increased Enterococcus populations by up to 33-fold. The findings suggest that limiting sugar during antibiotic courses could protect gut health and improve clinical outcomes, particularly for cancer patients undergoing stem cell transplants.

via Prevention|

#antibiotics #cancer-care #gut-health

science7 days ago•68 min saved

Enterobacteriaceae and diet drive gut microbial dominance

Researchers found that diet alone does not explain why some people have Prevotellaceae-dominant gut microbiomes while others have Bacteroidaceae-dominant ones. Using synthetic gut communities, they showed that Enterobacteriaceae, such as E. coli, synergize with specific dietary fibers like arabinan to help Segatella copri outcompete Bacteroidaceae. This interaction helps explain why Prevotellaceae-rich microbiomes are common in non-industrialized populations with plant-rich diets.

via Nature|

#bacteroidales #gut-health #microbiome

health8 days ago•1 min saved

Australian Study Links Persistent BV to Microbiome Failure and Partner Re-infection

Australian researchers identified two distinct pathways for recurrent bacterial vaginosis (BV): failure to clear the infection during treatment and re-infection from partners. Published in The Lancet, the study of 188 couples found that while concurrent partner treatment reduced recurrence by over 60%, approximately one-third of women did not achieve optimal vaginal microbiome recovery after a week of antibiotics, making them nearly three times more likely to relapse within four weeks.

via The Guardian|

#bacterial-vaginosis #health #lancet

science-and-technology8 days ago•15 min saved

AI System 'mHolmes' Uses Microbiome Data to Estimate Time of Death with High Accuracy

Researchers have developed an AI system called mHolmes that estimates the time since death by analyzing microbial changes on cadavers. Published in Nature Communications, the tool achieves an average error of less than two days, outperforming traditional methods that often err by three days or more. The system can also reconstruct microbial history for bodies discovered late or in fragmented states, offering a potential breakthrough for forensic investigations.

via Gizmodo|

#artificial-intelligence #forensic-science #microbiome

health-and-science10 days ago•6 min saved

Coffee reshapes gut bacteria, linking decaf to memory and regular to anxiety relief

A new study from University College Cork finds that both caffeinated and decaf coffee alter gut bacteria, influencing mood and cognition. Decaf improved memory, while caffeinated coffee reduced anxiety. The research highlights coffee's role in the gut-brain connection beyond caffeine.

via ScienceDaily|

#coffee-research #gut-brain-axis #health-and-science

health18 days ago•11 min saved

Beyond deodorant: living with bromhidrosis and its social toll

The article examines bromhidrosis, a condition where abnormal body odour stems from skin bacteria acting on sweat, often linked to overactive glands or microbiome changes (exacerbated by menopause and stress). It highlights the social and psychological impact—stigma, isolation, and discrimination—along with a range of management options (antibacterial hygiene, lifestyle changes, laser/waxing, Botox, miraDry) and the need for greater clinician awareness and compassion.

via The Guardian|

#body-odour #bromhidrosis #health

health20 days ago•15 min saved

Late-Life Allergies: The Immune System's Surprising New Triggers

Allergies can emerge at any age, not just in childhood. New-onset allergies can be sparked by infections like COVID-19 (which may increase allergy risk), other viruses, antibiotics that disrupt the gut microbiome, hormonal shifts during pregnancy or menopause, and even tick bites that cause meat allergies. While steps to support gut health and early inflammation control may help reduce risk, there is currently no guaranteed cure; researchers are pursuing immune-modulating therapies and vaccines to retrain the immune system.

via BBC|

#allergy #covid-19 #health

health22 days ago•3 min saved

ADHD Linked to a 48% Increase in Gut Problems, Large Review Finds

A large systematic review of 23 studies covering about 1.9 million people links ADHD to a 48% higher odds of experiencing functional gastrointestinal symptoms (eg, IBS, constipation, abdominal pain, diarrhea, indigestion, encopresis). While the exact cause isn’t established, potential factors include ADHD-related stress and emotional dysregulation, irregular eating, sensory food sensitivities, interoception differences, stimulant medications, sleep disturbances, and gut microbiome differences. Clinicians should consider GI symptoms when managing ADHD, as these issues can significantly affect quality of life.

via Euronews.com|

#adhd #gastrointestinal-symptoms #gut-brain-axis

health27 days ago•4 min saved

Could stomach bacterium H. pylori be linked to one-fifth of bowel cancers?

A new meta-analysis pooling 43 studies (nearly 49 million people) suggests Helicobacter pylori infection could be linked with about 22% of bowel cancers worldwide, corresponding to a 1.6-fold higher risk for those infected, though it does not prove causation. When limited to more rigorous population-based and cohort studies, the estimated share drops to around 12%. Biological links are plausible via chronic stomach inflammation and shifts in the gut microbiome, but the exact chain to colorectal cancer remains unproven. Some observational studies hint that eradicating H. pylori might lower later risk after about ten years, but no randomized trials confirm this; established prevention remains screening and healthy lifestyle. Further research is needed to determine causality and whether testing or treatment would reduce colorectal cancer incidence.

via The Conversation|

#cancer-risk #colorectal-cancer #h-pylori

science27 days ago•5 min saved

A 117-Year-Old’s Cells Show Youthful Clocks Hidden in an Aging Body

Researchers studying Maria Branyas Morera, the oldest known person, found a paradox in her biology: her cells carried clear signs of aging (short telomeres, pro-inflammatory immune features, and clonal hematopoiesis) while epigenetic clocks suggested her cells were about 23 years younger than her chronological age. Her gut microbiome was rich in Bifidobacterium, a pattern associated with youth and possibly linked to yogurt consumption. The study suggests that longevity and disease resistance may be partly separable processes, but it’s based on a single individual and requires larger cohorts for validation.

via Futura, le média qui explore le monde|

#aging #epigenetics #longevity

health-and-medicine28 days ago•8 min saved

Aging on two fronts: a 117-year-old's body shows signs of aging and protection

Researchers analyzed Maria Branyas, 117, using multi-omics and found a paradox: signs of extreme aging (short telomeres, pro-inflammatory immune profile) coexisting with protective traits (neuro-/cardioprotection genes, very low inflammation, beneficial gut bacteria, and an epigenetic age younger than her chronological age). The study, on a person without major disease, offers a rare view of aging itself and suggests interventions could target the biology of aging rather than specific diseases.

via Science Daily|

#aging #epigenetics #health-and-medicine

science29 days ago•50 min saved

Blueprint for AI-ready, standardized multi-omics in microbiome research

This Perspective argues that deciphering microbiome function requires coordinated, benchmarked, FAIR multi-omics workflows spanning metagenomics, metatranscriptomics, metaproteomics, and metabolomics. It reviews each layer’s strengths and limitations, highlights cross-omics integration challenges, and proposes a practical, tiered roadmap—foundational study design, integration and benchmarking, and ecosystem infrastructure—driven by community standards and open benchmarks to enable reproducible, interpretable, and AI-ready insights across diverse environments.

via Nature|

#data-integration #microbiome #multi-omics

science1 month ago•21 min saved

Urinary Bacteria May Synthesize Testosterone Near the Prostate, Hinting at Cancer Links

A study shows the urinary tract bacterium Actinobaculum massiliense can convert the steroid precursor DHEA into testosterone, revealing a microbial route to androgen production near the prostate. While not claiming bacteria cause cancer or produce meaningful hormone levels in people, the finding suggests a possible link to androgen-driven prostate cancer and highlights the need for further research into the urobiome’s role in this disease.

via ZME Science|

#androgen #dhea #microbiome

health1 month ago•17 min saved

Wearable fart tracker aims to map digestion and gut health

A disc-shaped sensor snaps into the back of underwear to measure hydrogen in farts, forming part of the Human Flatus Atlas. It lets wearers go about their day while researchers study how gut microbes respond to diet and how fiber influences gas production, with the goal of improving digestive health. Early studies found an average of about 32 farts over roughly a week of wear; a later study with 500+ volunteers tracked 22 hours a day for 3 to 30 days. The device is not medical-grade yet, but scientists hope it could help diagnose or monitor GI conditions and inform personalized dietary or microbiome-focused therapies. Still, fart frequency alone isn’t a diagnostic tool.

via eastidahonews.com|

#digestive-health #flatulence #gut-health