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Microbiome

All articles tagged with #microbiome

Gut Microbiome Transplants Show Early Hints of Peanut Allergy Tolerance
health1 day ago

Gut Microbiome Transplants Show Early Hints of Peanut Allergy Tolerance

A small Boston Children’s Hospital study used donor gut bacteria delivered via “poop pills” to people with severe peanut allergies; several participants showed increased tolerance to peanuts months later, especially after antibiotics to clear existing gut microbes. The results suggest a microbiome-based pathway affecting immune tolerance, with follow-up trials exploring teen capsule transplants and combining microbiome therapy with peanut immunotherapy.

via LiveNOW from FOX|
#bile-salts#fecal-transplant#health
Gut Bacteria Transplants Offer Sleep Gains in Small Insomnia Trial
health2 days ago

Gut Bacteria Transplants Offer Sleep Gains in Small Insomnia Trial

In a small study, adults with chronic insomnia received fecal microbiota transplant capsules after a two‑day course of antibiotics. Sleep efficiency rose from about 79% to 93% after one month, and time awake at night dropped from 79 to 17 minutes; self-reported sleep improvements persisted for months. The placebo group saw little change, but antibiotics and the small sample size mean it’s unclear how much of the effect is due to the transplants, underscoring the need for larger trials.

via New York Post|
#fecal-microbiota-transplant#gut-health#health
A Day in 50g of Fiber: How a Gut Health Scientist Feeds Her Microbiome
health3 days ago

A Day in 50g of Fiber: How a Gut Health Scientist Feeds Her Microbiome

Megan Rossi, a gut health scientist and registered dietitian at King’s College London, aims for 50–60 grams of fiber daily—above the UK guideline of 30g—believing this level could boost mood and gut health by feeding the gut’s bacteria. Her day is built around high-fiber choices: a kefir-soaked overnight oats breakfast with seeds, fruit, and nuts; a lunch bowl aligning with her “Super Six” plant-based groups (grains, legumes, vegetables, nuts/seeds, fruits, herbs/spices), plus yogurt and olive oil; an afternoon smoothie packed with frozen fruits/vegetables and kefir; and a dinner stir-fry with protein, vegetables, and legumes, followed by frozen berries with kefir for dessert. She emphasizes gradual fiber increases to minimize bloating and relies on meal planning to hit fiber targets, highlighting the microbiome’s role in digestion, mood, and overall health while noting that more research is needed.

via Business Insider|
#fiber#gut-health#health
Social bonds steer wild horses' gut microbes, outpacing bloodlines
science6 days ago

Social bonds steer wild horses' gut microbes, outpacing bloodlines

On Sable Island off Nova Scotia, feral horses from the same herd share more similar gut microbiomes than would be expected by genetics alone, and social interactions appear to shape these microbial communities even more than kinship, with microbiome differences linked to survival; the study suggests microbiome-mediated adaptive evolution in a wild population, though it remains preliminary and focused on one island.

via Space Daily|
#gut-bacteria#host-genetics#microbiome
Gut Microbes May Mirror Psychopathic Traits, Early Study Finds
science11 days ago

Gut Microbes May Mirror Psychopathic Traits, Early Study Finds

A small, first-of-its-kind study from University of Porto suggests a link between gut microbiota and psychopathic traits: stronger psychopathy scores correlated with higher abundances of Allisonella, Prevotella, and C. evryensis and lower levels of T. vincentii. The findings are correlational and based on a small, self-reported sample, so causality cannot be established; authors caution that further, cross-regional research is needed to understand the microbiome–brain connection and potential bidirectional effects.

via Yahoo|
#gut-brain-axis#inflammation#microbiome
Viome Gut Test Upends My Diet: Avoiding Cruciferous Veggies, Embracing Dairy
health12 days ago

Viome Gut Test Upends My Diet: Avoiding Cruciferous Veggies, Embracing Dairy

A wellness review of Viome’s Gut Intelligence Test ($279) details an at‑home stool analysis that analyzes 2,500 biomarkers and provides 370 personalized food recommendations. The author is surprised to learn she should avoid cruciferous vegetables due to elevated sulfide gas production and should pair calcium-rich foods with high-oxalate items to improve absorption, with most scores in the green but some red flags. She also starts Viome Precision Supplements (~$169/month) and a Gut Formula probiotic, reporting improved digestion, more energy, and better mood/sleep after a few weeks. The piece concludes the test is worth it for health‑mocused readers willing to change their diet, though it’s not diagnostic and retesting every six months is advised, backed by accessible resources and guidance from Viome.

via New York Post|
#at-home-testing#gut-health#health
Gut microbes tied to psychopathic traits in preliminary study
science12 days ago

Gut microbes tied to psychopathic traits in preliminary study

A small, non-peer-reviewed study from the University of Porto reports a correlational link between specific gut and oral bacteria (Allisonella, Prevotella, and C. evryensis) and psychopathic traits in 200 adults. The researchers caution that the study is correlational with a small sample and potential biases, so causality cannot be established and results may vary by geography or self-report biases; more research is needed to explore how the gut microbiome might influence extreme behavior, if at all.

via Futurism|
#allisonella#gut-brain-axis#microbiome
Gut Microbiome Signals Tied to Psychopathic Traits in Early Study
science14 days ago

Gut Microbiome Signals Tied to Psychopathic Traits in Early Study

In an early Translational Psychiatry study, researchers analyzed 200 healthy adults and found that higher levels of certain gut and oral bacteria (Allisonella, Prevotella, Cloacibacillus evryensis) correlated with stronger psychopathic traits, while Treponema vincentii showed a negative association. The work does not show causation and is not yet peer-reviewed, but suggests microbiota could serve as biomarkers for psychopathic traits and potentially influence behavior via inflammation or neurotransmitter pathways like GABA.

via ScienceAlert|
#biomarkers#gut-brain-axis#microbiome
Engineered bean gum shows promise against mouth and throat cancer risk
health15 days ago

Engineered bean gum shows promise against mouth and throat cancer risk

Scientists bioengineered a lablab bean gum containing an antiviral protein that cuts HPV levels by up to 93% in saliva and, when fortified with protegrin, nearly eliminates two cancer-associated oral bacteria (Pg and Fn), suggesting use as an adjuvant therapy or preventive measure for squamous cell carcinoma of the mouth and throat while preserving beneficial oral microbes.

via New York Post|
#cancer#chewing-gum#health
Birth order may steer health risks across life, large study finds
health18 days ago

Birth order may steer health risks across life, large study finds

A large study of over 10 million two-child families links birth order to disease risk across many conditions: first-borns show higher odds of neurodevelopmental issues (autism, ADHD), OCD, Tourette syndrome, allergies and acne, while younger siblings are more prone to substance abuse, gastrointestinal problems, and certain infections such as herpes zoster. The authors suggest immune and microbial exposure differences, plus social factors, with closer age gaps strengthening the microbial-sharing effect.

via Euronews|
#allergies#birth-order#health
Diet–Gut Allies Amplify Cancer Immunotherapy in Obesity
science1 month ago

Diet–Gut Allies Amplify Cancer Immunotherapy in Obesity

A Nature study shows that obesity-related immunotherapy responses are driven by the diet–gut microbiome axis rather than metabolic dysfunction alone. Using 12 mouse diet models, researchers found obesogenic diets foster a stable gut microbiota that can restore anti-PD-1 sensitivity after short diet changes or fecal microbiota transplantation from non-responders. Monocolonization with beneficial bacteria like Lactobacillus johnsonii, paired with an obesogenic diet, enhanced tumor regression via microbiota-derived aromatic amino acid metabolites. In human-to-mouse FMT, high-BMI donors boosted ICI efficacy versus normal-BMI donors, and an obesogenic diet could restore sensitivity after FMT from a non-responder. The work suggests diet–microbiome synergy could be leveraged to improve ICI outcomes and guide FMT-based strategies.

via Nature|
#diet#immunotherapy#microbiome
Digestive cancers show distinct microbiomes, large study finds
science1 month ago

Digestive cancers show distinct microbiomes, large study finds

A large-scale analysis of Genomics England’s 100,000 Genomes Project used stringent methods to separate genuine microbial signals from lab contamination. The study found that most cancers (including brain, breast and kidney cancers) do not have a microbiome distinguishable from background, suggesting earlier reports may reflect contamination. In contrast, mouth, esophagus, stomach and colorectal cancers showed clear, consistent microbial life, including bacteria, viruses, fungi and archaea, with microbe communities varying by tumor location and subtype. The team released their data and a list of confidently present microbes to help other researchers apply the rigorous approach, with implications for understanding how microbiomes influence tumor development, treatment response, and potentially improving GI cancer diagnosis and early detection.

via The Conversation|
#cancer#contamination#genomics