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Science And Tech

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Old seizure medicine shows potential to prevent Alzheimer's decades before symptoms
science-and-tech1 month ago

Old seizure medicine shows potential to prevent Alzheimer's decades before symptoms

Northwestern University researchers report that levetiracetam, a long-used anti-seizure drug, may prevent Alzheimer’s by blocking the production of amyloid-beta 42, the protein linked to plaques, with results seen in animal models and cultured human neurons (and post-mortem Down syndrome brain tissue). If taken decades before symptoms, it could theoretically slow or prevent disease, though there are no human trials yet and the evidence is observational; researchers caution that the drug would need to start very early and are pursuing longer-lasting formulations and trials, including in genetic forms of Alzheimer’s.

Hidden Plates at U.S. Seismic Hotspot Could Spark Magnitude-8 Quakes
science-and-tech2 months ago

Hidden Plates at U.S. Seismic Hotspot Could Spark Magnitude-8 Quakes

Scientists found that California’s Mendocino Triple Junction, a hotspot where three tectonic plates meet, actually comprises five moving plates (including two hidden ones). Using a network of seismometers, researchers revealed under-surface configurations and a shallower subduction zone, suggesting the area’s quake risk may be higher than previously thought and could trigger magnitude-8 earthquakes, with implications for millions in the region and offering context for past events like the 1992 Humboldt County quake.